You will need to use a UTF-8 database so you can store the Unicode characters you will need to allow Russian and Chineese. I would suggest MySQL >4.1.3 or PostgreSQL.
The site setup is straighforward.
http://ez.no/ez_publish/documentation/configuration/configuration/language_and_charset/how_to_setup_a_multilingual_site http://ez.no/ez_publish/documentation/configuration/configuration/language_and_charset/unicode_with_ez_publish
Good luck
Tony Wood : twitter.com/tonywood
Vision with Technology
Experts in eZ Publish consulting & development
Also note that as eZ is today it's laid out for having different siteaccesses for the different languages. But still works to setup translations of individual articles, it's just not that very well explained anywhere. Will add in to another thread here how to list your translations which I troubled with for a while.
Plus it is not made to have the site in English and have articles that do not exist in English in other languages. Sure can find a workaround for that but it's a thing to have in mind - no non-english if there isn't an english version.